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Researchers uncovered how shifting levels of a brain protein called KCC2 can reshape the way cues become linked with rewards, sometimes making habits form more quickly or more powerfully than expected. When this protein drops, dopamine neurons fire more intensely, strengthening new associations in ways that resemble how addictive behaviors take hold. Rat studies showed that even brief, synchronized bursts of neural activity can amplify reward learning, offering insight into why everyday triggers, like a morning routine, can provoke strong cravings.
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Researchers have uncovered surprising evidence that the deep ocean’s carbon-fixing engine works very differently than long assumed. While ammonia-oxidizing archaea were thought to dominate carbon fixation in the sunless depths, experiments show that other microbes—especially heterotrophs—are doing far more of the work than expected. This discovery reshapes our understanding of how carbon moves through the deep ocean and stabilizes Earth’s climate.
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Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell death—to survive treatment. Instead of dying, these “persister cells” leverage this sublethal signal to regrow. Because the mechanism is non-genetic, it appears much earlier than typical resistance mutations. Targeting this enzyme could help stop tumors from returning.
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Obesity accelerates the rise of Alzheimer’s-related blood biomarkers far more rapidly than previously recognized. Long-term imaging and plasma data show that obese individuals experience much faster increases in proteins linked to neurodegeneration and amyloid buildup. Surprisingly, blood tests detected these changes earlier than PET scans. The results point to obesity as a major, modifiable contributor to Alzheimer’s progression.
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Uranus and Neptune may not be the icy worlds we’ve long imagined. A new Swiss-led study uses innovative hybrid modeling to reveal that these planets could just as easily be dominated by rock as by water-rich ices. The findings also help explain their bizarre, multi-poled magnetic fields and open the door to a wider range of possible interior structures. But major uncertainties remain, and only future space missions will be able to uncover what truly lies beneath their blue atmospheres.